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Ralph A Pietrofesa Selected Research

secoisolariciresinol diglucoside

11/2020Synthetic Secoisolariciresinol Diglucoside Attenuates Established Pain, Oxidative Stress and Neuroinflammation in a Rodent Model of Painful Radiculopathy.
1/2019Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits Libby amphibole fiber-induced acute inflammation in mice.
3/2016Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605).
2/2016Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice.

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Ralph A Pietrofesa Research Topics

Disease

10Inflammation (Inflammations)
10/2021 - 01/2014
7Neoplasms (Cancer)
03/2018 - 01/2016
4Malignant Mesothelioma
07/2016 - 01/2016
3Asbestosis
10/2021 - 07/2016
3Mesothelioma
10/2021 - 03/2016
3Lung Injury
11/2017 - 01/2014
2Autoimmune Diseases (Autoimmune Disease)
10/2021 - 01/2019
2Hyperoxia
06/2016 - 01/2014
2Fibrosis (Cirrhosis)
01/2014 - 09/2013
1Lung Diseases (Lung Disease)
10/2021
1Esophagitis
10/2021
1Radiation Pneumonitis
10/2021
1Radiculopathy (Radiculopathy, Cervical)
11/2020
1Neuroinflammatory Diseases
11/2020
1Pain (Aches)
11/2020
1Wounds and Injuries (Trauma)
11/2020
1Pleural Diseases
01/2019
1Primary Graft Dysfunction
01/2019
1Infections
01/2018
1Pneumonia (Pneumonitis)
11/2017
1Lung Neoplasms (Lung Cancer)
07/2016
1Adenoma (Adenomas)
11/2015
1Colorectal Neoplasms (Colorectal Cancer)
11/2015
1Type 2 Diabetes Mellitus (MODY)
11/2015
1Cystic Fibrosis (Mucoviscidosis)
05/2015
1Pulmonary Fibrosis (Fibrosing Alveolitis)
09/2013

Drug/Important Bio-Agent (IBA)

8AsbestosIBA
10/2021 - 01/2016
6LGM2605IBA
10/2021 - 03/2016
5AntioxidantsIBA
11/2020 - 05/2015
4secoisolariciresinol diglucosideIBA
11/2020 - 02/2016
3LignansIBA
10/2021 - 05/2015
3CytokinesIBA
11/2017 - 02/2016
3Proteins (Proteins, Gene)FDA Link
06/2016 - 09/2013
2Amphibole AsbestosIBA
10/2021 - 01/2019
2Peroxidase (Myeloperoxidase)IBA
08/2021 - 01/2018
2Biomarkers (Surrogate Marker)IBA
11/2017 - 05/2015
2InflammasomesIBA
01/2017 - 01/2016
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2017 - 03/2016
2Hydroxyproline (4 Hydroxyproline)IBA
01/2014 - 09/2013
1LipidsIBA
05/2021
13-nitrotyrosineIBA
11/2020
1Hypochlorous Acid (Hypochlorite)IBA
01/2018
1Protons (Proton)IBA
11/2017
1Biological ProductsIBA
11/2017
1KL4 surfactantIBA
11/2017
1Reactive Nitrogen SpeciesIBA
01/2017
1Caspase 3 (Caspase-3)IBA
06/2016
1Annexin A5IBA
06/2016
1HMGB1 Protein (HMG1)IBA
02/2016
1Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
01/2016
1Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
01/2016
1Metformin (Glucophage)FDA LinkGeneric
11/2015
1BiguanidesIBA
11/2015
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
05/2015
1NitritesIBA
01/2014
1Malondialdehyde (Propanedial)IBA
01/2014
1Aligeron (AS 2)IBA
09/2013

Therapy/Procedure

2Radiotherapy
10/2021 - 11/2017
2Chemoprevention
03/2016 - 02/2016
2Therapeutics
01/2016 - 01/2016
1Artificial Respiration (Mechanical Ventilation)
01/2019
1Length of Stay
01/2019